Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430467 | 0.90 | ALDH1A1 (0.34) | HTTGAAUPP1MAPT | |
| SCHEMBL9016402 | 0.89 | UPP1 (0.38) | HTTUPP1 | |
| SCHEMBL7541334 | 0.89 | GAA (0.33) | GAA | |
| SCHEMBL8426877 | 0.86 | UPP1 (0.40) | PNPUPP1 | |
| SCHEMBL8430830 | 0.84 | PNP (0.33) | HTTPNP | |
| SCHEMBL8426736 | 0.83 | GAA (0.34) | GAAMAPT | |
| SCHEMBL7534059 | 0.82 | ALDH1A1 (0.46) | GAAMAPT | |
| SCHEMBL9266049 | 0.79 | UPP1 (0.40) | UPP1 | |
| SCHEMBL8430942 | 0.79 | GAA (0.38) | HTTGAAMAPT | |
| SCHEMBL8760223 | 0.79 | HTT (0.33) | HTTPNPGAAUPP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |