Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016418 | 0.81 | CYP1A2 (0.47) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL9016492 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP2D6NPSR1SRCLMNA | |
| SCHEMBL18901910 | 0.71 | CYP1A2 (0.45) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL25404016 | 0.71 | CYP1A2 (0.61) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL1302046 | 0.69 | CYP1A2 (0.59) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL25121338 | 0.69 | CYP1A2 (0.59) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL10332554 | 0.68 | PLA2G7 (0.67) | LMNAKMT2A | |
| SCHEMBL18526631 | 0.68 | CYP1A2 (0.45) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL622284 | 0.67 | CYP1A2 (0.57) | CYP1A2CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL10402902 | 0.67 | CYP1A2 (0.57) | CYP1A2CYP2D6SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |