Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016511 | 1.00 | POLB (0.53) | POLBSMN1; SMN2ACMSDKDM4EKMT2A | |
| SCHEMBL2554736 | 0.84 | PTGDR2 (0.62) | POLBSMN1; SMN2ACMSDKMT2ALMNA | |
| SCHEMBL6744642 | 0.82 | SMN1; SMN2 (0.70) | POLBSMN1; SMN2ACMSDKDM4EKMT2A | |
| SCHEMBL9016535 | 0.80 | ACMSD (0.52) | POLBSMN1; SMN2ACMSDKDM4EKMT2A | |
| SCHEMBL9016509 | 0.80 | ACMSD (0.52) | POLBSMN1; SMN2ACMSDKDM4EKMT2A | |
| SCHEMBL2161928 | 0.80 | LMNA (0.62) | SMN1; SMN2KDM4ELMNAHPGDTSHR | |
| SCHEMBL2161924 | 0.80 | LMNA (0.62) | SMN1; SMN2KDM4ELMNAHPGDTSHR | |
| SCHEMBL8695727 | 0.80 | LMNA (0.62) | SMN1; SMN2KDM4ELMNAHPGDTSHR | |
| SCHEMBL30656544 | 0.80 | LMNA (0.62) | SMN1; SMN2KDM4ELMNAHPGDTSHR | |
| SCHEMBL6743332 | 0.76 | POLB (0.62) | POLBSMN1; SMN2KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |