Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016544 | 1.00 | AKR1B1 (0.44) | AKR1B1HPGDALDH1A1TDP1CXCL8 | |
| SCHEMBL8343067 | 0.83 | AKR1B1 (0.46) | AKR1B1ALDH1A1TDP1CXCL8BCAT2 | |
| SCHEMBL8416291 | 0.83 | AKR1B1 (0.46) | AKR1B1ALDH1A1TDP1CXCL8BCAT2 | |
| SCHEMBL9016420 | 0.83 | AKR1B1 (0.46) | AKR1B1ALDH1A1TDP1CXCL8BCAT2 | |
| SCHEMBL8338530 | 0.78 | AKR1B1 (0.52) | AKR1B1HPGDALDH1A1TDP1CXCL8 | |
| SCHEMBL9016478 | 0.78 | AKR1B1 (0.52) | AKR1B1HPGDALDH1A1TDP1CXCL8 | |
| SCHEMBL9016481 | 0.78 | AKR1B1 (0.52) | AKR1B1HPGDALDH1A1TDP1CXCL8 | |
| SCHEMBL10332554 | 0.72 | PLA2G7 (0.67) | HPGDALDH1A1PLA2G7MEN1KMT2A | |
| SCHEMBL115054 | 0.72 | SRC (0.58) | AKR1B1TDP1CXCL8BCAT2SRC | |
| SCHEMBL156765 | 0.71 | AKR1B1 (0.55) | AKR1B1HPGDTDP1CXCL8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |