Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606905 | 0.90 | MEN1 (0.47) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL6798131 | 0.84 | ALDH1A1 (0.50) | MAPTLMNACASP1ALDH1A1HTT | |
| SCHEMBL30958584 | 0.80 | ALDH1A1 (0.44) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL1185918 | 0.80 | ALDH1A1 (0.44) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL10511114 | 0.78 | CHEK1 (0.39) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL8155555 | 0.77 | KDM4E (0.42) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL10512661 | 0.76 | CHEK1 (0.38) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL10516112 | 0.76 | ALDH1A1 (0.41) | MAPTLMNAMAPK1CASP1CASP7 | |
| Acetic Acid SCHEMBL8870017 | 0.76 | ALDH1A1 (0.41) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL30736446 | 0.76 | MEN1 (0.41) | MAPTLMNAMAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481441-B1 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN SEIYAKU KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5244892-A | Pseudomonas | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0481441-A2 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |