Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577670 | 0.77 | SLC6A3 (0.65) | SLC6A3ALDH1A1ALKBH5PDPK1 | |
| Hydrochloric Acid SCHEMBL2577794 | 0.75 | SLC6A3 (0.62) | SLC6A3ALDH1A1ALKBH5PDPK1 | |
| SCHEMBL9016828 | 0.73 | SLC6A3 (0.51) | SLC6A3ALDH1A1LMNA | |
| SCHEMBL6691161 | 0.69 | SLC6A3 (0.56) | SLC6A3ALDH1A1ALKBH5PDPK1LMNA | |
| SCHEMBL9016806 | 0.69 | SLC6A3 (0.55) | SLC6A3ALKBH5MEN1KMT2A | |
| SCHEMBL10334603 | 0.68 | PDPK1 (0.60) | SLC6A3MEN1KMT2APDPK1 | |
| SCHEMBL6250273 | 0.68 | SLC6A3 (0.54) | SLC6A3MEN1KMT2APDPK1 | |
| SCHEMBL23215107 | 0.67 | KMT2A (0.53) | SLC6A3ALDH1A1ALKBH5KMT2APDPK1 | |
| SCHEMBL1121660 | 0.67 | SLC6A3 (0.66) | SLC6A3 | |
| SCHEMBL30434120 | 0.67 | SLC6A3 (0.49) | SLC6A3ALDH1A1ALKBH5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571825-A | Method of selectively inhibiting prostaglandin G/H synthase-2 | WARNER-LAMBERT COMPANY (US) | 1996-11-05 | — | — | US | disclosed |