SCHEMBL9016828

SCHEMBL9016828

Cc1ccc(C(SCC(=O)O)c2ccc(C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.51
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
SLC6A4 P31645 1/20 0.49
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2577670 0.83 SLC6A3 (0.65) SLC6A3ALDH1A1SLC6A4FFAR1
SCHEMBL9016798 0.82 SLC6A3 (0.46) SLC6A3
SCHEMBL16011837 0.82 ALDH1A1 (0.51) SLC6A3ALDH1A1SLC6A4
SCHEMBL16011814 0.82 SLC6A3 (0.47) SLC6A3SLC6A4
SCHEMBL9016825 0.82 ALDH1A1 (0.54) SLC6A3ALDH1A1GAAMAPTSLC6A4
Hydrochloric Acid SCHEMBL2577794 0.82 SLC6A3 (0.62) SLC6A3ALDH1A1SLC6A4FFAR1
SCHEMBL11446798 0.80 FFAR1 (0.48) ALDH1A1LMNAGAAMAPTFFAR1
SCHEMBL9016806 0.79 SLC6A3 (0.55) SLC6A3SLC6A4FFAR1
SCHEMBL6691161 0.76 SLC6A3 (0.56) SLC6A3ALDH1A1LMNASLC6A4
SCHEMBL9016817 0.73 SLC6A3 (0.46) SLC6A3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571825-A Method of selectively inhibiting prostaglandin G/H synthase-2 WARNER-LAMBERT COMPANY (US) 1996-11-05 US disclosed