SCHEMBL9016847

SCHEMBL9016847

CCC1CCCCN1CCCCCc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 1/20 0.56
SIGMAR1 Q99720 3/20 0.55
SPHK2 Q9NRA0 2/20 0.52
SPHK1 Q9NYA1 2/20 0.52
ALDH1A1 P00352 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HSD17B10 Q99714 1/20 0.51
OPRD1 P41143 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4339380 0.86 SIGMAR1 (0.54) SIGMAR1
SCHEMBL5888789 0.86 SIGMAR1 (0.55) SIGMAR1
SCHEMBL5888846 0.81
SCHEMBL10913078 0.81 SIGMAR1 (0.44) MEN1NPC1RAB9AKMT2ASIGMAR1
SCHEMBL28101802 0.81 KCNH2 (0.57) KMT2ASPHK2SPHK1
SCHEMBL12128324 0.80 MEN1 (0.52) MEN1NPC1RAB9AKMT2ASIGMAR1
SCHEMBL10911173 0.79 SIGMAR1 (0.45) MEN1NPC1RAB9AKMT2ASIGMAR1
SCHEMBL10911231 0.79 MEN1 (0.47) MEN1NPC1RAB9AKMT2ASPHK2
SCHEMBL24447814 0.79 MAPK1 (0.59) MEN1NPC1RAB9AKMT2AALDH1A1
SCHEMBL11990423 0.79 MAPK1 (0.59) MEN1NPC1RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed