Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27264898 | 0.92 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9432598 | 0.89 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL9432600 | 0.89 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL5888789 | 0.88 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL12128324 | 0.88 | MEN1 (0.52) | SIGMAR1 | |
| SCHEMBL9016847 | 0.86 | MEN1 (0.56) | SIGMAR1 | |
| SCHEMBL9820990 | 0.86 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL5888846 | 0.84 | — | — | |
| SCHEMBL12128577 | 0.84 | MEN1 (0.53) | — | |
| SCHEMBL8698471 | 0.82 | HMOX1 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549950-B1 | METHODS FOR IDENTIFYING GLUCOSE UPTAKE MODULATORS | BIOVITRUM AB PUBL (SE) | 2009-02-11 | — | — | EP | disclosed |
| EP-1549950-A1 | METHODS FOR IDENTIFYING GLUCOSE UPTAKE MODULATORS | BIOVITRUM AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| US-20040092456-A1 | Methods for identifying glucose uptake modulators | HB KATZ RESEARCH AND EDUCATION (SE) | 2004-05-13 | — | — | US | disclosed |
| WO-2004001410-A1 | METHODS FOR IDENTIFYING GLUCOSE UPTAKE MODULATORS | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | disclosed |
| US-6229000-B1 | NUCLEOTIDE SEQUENCES; DRUG SCREENING FOR CHANNEL BLOCKERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| EP-0556651-B2 | Human neuronal beta-subunits of voltage-dependent calcium channels and use of the same | BAYER AG (DE) | 1999-11-03 | — | — | EP | disclosed |
| US-5643750-A | Human neuronal beta subunits of voltage-operated calcium channels and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-01 | — | — | US | disclosed |
| EP-0507170-B1 | Calcium channel subtype specific of human neuronal tissue and its use | BAYER AG (DE) | 1997-01-15 | — | — | EP | disclosed |
| EP-0556651-A2 | Human neuronal beta-subunits of voltage-dependent calcium channels and use of the same | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0507170-A2 | Calcium channel subtype specific of human neuronal tissue and its use | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |