Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397302 | 0.74 | TSHR (0.34) | TSHR | |
| SCHEMBL19333598 | 0.72 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL13419032 | 0.72 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL13454198 | 0.72 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL3503019 | 0.72 | — | — | |
| SCHEMBL992095 | 0.72 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL5772368 | 0.71 | TSHR (0.40) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL366543 | 0.70 | TGFBR1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL14079329 | 0.70 | — | — | |
| SCHEMBL18689521 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453010-B1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INT RESEARCH (NL) | 1996-06-05 | — | — | EP | disclosed |
| US-5135976-A | MELT STABILIZED POLYKETONE COPOLYMER COMPOSITIONS CONTAINING GLYCIDYL ETHER COMPOUND | SHELL OIL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| US-5115002-A | Carbon monoxide-ethylene copolymer and a zeolite stabilizer | SHELL OIL COMPANY (US) | 1992-05-19 | — | — | US | disclosed |
| US-5075422-A | PROCESS FOR THE PREPARATION OF POLYKETONE COPOLYMERS AND COPOLYMER WASH WITH LIQUID COMPRISING CARBOXYLIC COMPOUND | SHELL OIL COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0453010-A1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |