Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL366542 | 0.73 | TGFBR1 (0.46) | TGFBR1TSHRRXFP1ALDH1A1 | |
| SCHEMBL30214 | 0.72 | TGFBR1 (0.44) | TGFBR1TSHRRXFP1ALDH1A1 | |
| SCHEMBL3388819 | 0.72 | TGFBR1 (0.44) | TGFBR1TSHRRXFP1ALDH1A1 | |
| SCHEMBL339839 | 0.70 | TSHR (0.35) | TGFBR1TSHRRXFP1 | |
| SCHEMBL9016917 | 0.70 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL8973234 | 0.69 | TSHR (0.36) | TGFBR1TSHRRXFP1ALDH1A1 | |
| SCHEMBL50197 | 0.69 | — | — | |
| SCHEMBL18660317 | 0.69 | TSHR (0.41) | TGFBR1TSHRALDH1A1 | |
| Urea SCHEMBL1784480 | 0.68 | TGFBR1 (0.40) | TGFBR1TSHRRXFP1 | |
| SCHEMBL28408867 | 0.68 | TGFBR1 (0.40) | TGFBR1TSHRRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | TGFBR1 4012/4885TSHR 4451/4885RXFP1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.