Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.33 |
| ▸ | CDC25A | P30304 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603821 | 0.76 | ALDH1A1 (0.36) | S100A4KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL9016932 | 0.60 | KDM4E (0.31) | KDM4E | |
| SCHEMBL28216738 | 0.60 | S100A4 (0.62) | PDK2S100A4KDM4EALDH1A1LMNA | |
| SCHEMBL1277008 | 0.59 | S100A4 (0.33) | S100A4 | |
| SCHEMBL8737319 | 0.58 | S100A4 (0.48) | PDK2S100A4KDM4ELMNAMAPT | |
| SCHEMBL30004248 | 0.58 | APEX1 (0.48) | PDK2CDC25ACDC25BMAP2K7ALDH1A1 | |
| SCHEMBL5329061 | 0.58 | APEX1 (0.48) | PDK2CDC25ACDC25BMAP2K7ALDH1A1 | |
| SCHEMBL14939203 | 0.57 | S100A4 (0.47) | PDK2CDC25ACDC25BPTPN1S100A4 | |
| SCHEMBL18415976 | 0.57 | APEX1 (0.47) | PDK2CDC25ACDC25BMAP2K7ALDH1A1 | |
| SCHEMBL29612259 | 0.57 | S100A4 (0.65) | PDK2S100A4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504232-A | Process for the preparation of an olefin polymer using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |