Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15393160 | 0.98 | LMNA (0.66) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL3746846 | 0.93 | SMN1; SMN2 (0.73) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL380994 | 0.93 | CA1 (0.73) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL3310683 | 0.92 | LMNA (0.64) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL7251467 | 0.91 | LOXL2 (0.83) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL185028 | 0.91 | MEN1 (0.61) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL1368686 | 0.91 | NPC1 (0.78) | LMNAHPGDLOXL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1169317 | 0.91 | SMN1; SMN2 (0.71) | LMNAHPGDLOXL2NPC1RAB9A | |
| SCHEMBL2655924 | 0.90 | HPGD (0.62) | LMNAHPGDLOXL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16506822 | 0.89 | CA1 (0.70) | LMNAHPGDLOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328843-B1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2022-10-26 | — | — | EP | disclosed |
| CN-109476705-A | novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20180251437-A1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-09-06 | — | — | US | disclosed |
| EP-3328843-A1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017018803-A1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-02-02 | — | — | WO | disclosed |
| WO-2017018803-A1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-02-02 | — | — | WO | disclosed |
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5240976-A | For automobile, wire and cable uses | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251437-A1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC1, HDAC6, HDAC2 | LMNA 3360/4885HPGD 534/4885LOXL2 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.