Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017220 | 0.87 | PNMT (0.45) | PNMTADRA2ACYP19A1TSHRLMNA | |
| SCHEMBL11420023 | 0.82 | CYP19A1 (0.44) | PNMTADRA2ACYP19A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL19357973 | 0.75 | PNMT (0.44) | PNMTADRA2ACYP19A1TSHRLMNA | |
| SCHEMBL383577 | 0.74 | PNMT (0.74) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1786988 | 0.73 | PNMT (0.72) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL212845 | 0.71 | CYP19A1 (0.81) | CYP19A1TSHRLMNAVCAM1CYP3A4 | |
| SCHEMBL6294929 | 0.70 | PNMT (0.58) | PNMTADRA2ACYP19A1VCAM1ADRA2B | |
| Nitric Acid SCHEMBL4718613 | 0.70 | PNMT (0.68) | PNMTADRA2AADRA2BADRA2C | |
| Nitric Acid SCHEMBL4718617 | 0.70 | PNMT (0.68) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL24773896 | 0.69 | PNMT (0.56) | PNMTADRA2ACYP19A1TSHRVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268093-B1 | 5-Nitrobenzo[de]isoquinoline-1,3 diones, their preparation and use | KNOLL AG (DE) | 1992-05-13 | — | — | EP | claimed |
| US-5552544-A | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use | KNOLL AG (DE) | 1996-09-03 | — | — | US | disclosed |