Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017103 | 0.87 | PNMT (0.49) | PNMTADRA2ATSHRTDP1LMNA | |
| SCHEMBL5376486 | 0.82 | TDP1 (0.49) | PNMTADRA2ATSHRTDP1LMNA | |
| SCHEMBL29903867 | 0.74 | TSHR (0.58) | TSHRTDP1LMNAMEN1KMT2A | |
| SCHEMBL10788183 | 0.74 | TSHR (0.58) | TSHRTDP1LMNAMEN1KMT2A | |
| SCHEMBL255918 | 0.73 | TSHR (0.50) | PNMTTSHRLMNAMEN1KMT2A | |
| SCHEMBL5274188 | 0.71 | PNMT (0.51) | PNMTADRA2ATSHRTDP1LMNA | |
| SCHEMBL383577 | 0.71 | PNMT (0.74) | PNMTADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL9757191 | 0.70 | PNMT (0.50) | PNMTADRA2ATSHRTDP1LMNA | |
| Hydrochloric Acid SCHEMBL31335791 | 0.70 | PNMT (0.50) | PNMTADRA2ATSHRTDP1LMNA | |
| SCHEMBL11420023 | 0.70 | CYP19A1 (0.44) | PNMTADRA2ATSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552544-A | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use | KNOLL AG (DE) | 1996-09-03 | — | — | US | disclosed |