Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.59 |
| ▸ | RAD52 | P43351 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017091 | 0.85 | FTO (0.59) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL10340131 | 0.83 | MEN1 (0.82) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL10340125 | 0.82 | MEN1 (0.80) | KMT2AMEN1POLBPABPC1RAD52 | |
| Hydrochloric Acid SCHEMBL10898438 | 0.82 | MEN1 (0.80) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL9017063 | 0.77 | MEN1 (0.72) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL9017195 | 0.76 | MEN1 (0.71) | KMT2AMEN1POLBPABPC1RAD52 | |
| Pinafide SCHEMBL18697 | 0.75 | MEN1 (1.00) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL10340133 | 0.74 | POLB (0.67) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL11552380 | 0.74 | MEN1 (0.98) | KMT2AMEN1POLBPABPC1RAD52 | |
| SCHEMBL9017061 | 0.73 | FTO (0.64) | KMT2AMEN1POLBPABPC1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552544-A | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use | KNOLL AG (DE) | 1996-09-03 | — | — | US | claimed |
| US-5552544-A | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use | KNOLL AG (DE) | 1996-09-03 | — | — | US | disclosed |
| EP-0268093-A1 | 5-Nitrobenzo[de]isoquinoline-1,3 diones, their preparation and use | KNOLL AG (DE) | 1988-05-25 | — | — | EP | disclosed |