SCHEMBL9017213

SCHEMBL9017213

CC(=CCCl)CCCC(C)(C)Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
SQLE Q14534 2/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017154 1.00 ALDH1A1 (0.36) ALDH1A1SQLEALOX15
SCHEMBL9709477 0.93 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9709475 0.93 ALDH1A1 (0.31) ALDH1A1
SCHEMBL10680113 0.93 SQLE (0.42) ALDH1A1SQLEALOX15
SCHEMBL10680108 0.93 SQLE (0.42) ALDH1A1SQLEALOX15
SCHEMBL10730519 0.85 PTPN1 (0.41) ALOX15
SCHEMBL10730516 0.85 PTPN1 (0.41) ALOX15
SCHEMBL21894289 0.83 ALOX15 (0.43) ALDH1A1SQLEALOX15
Trimethylammonium SCHEMBL10707348 0.79 CYP1A1 (0.35) ALDH1A1SQLEALOX15
SCHEMBL15484102 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011585-A None JP disclosed
EP-0414106-B1 Process for the preparation of terpenes EISAI CO LTD (JP) 1996-03-27 EP disclosed
US-5073659-A Alkylation, Grignard reagent, zinc chloride catalyst and coppe r compound EISAI CO., LTD. (JP) 1991-12-17 US disclosed
EP-0414106-A2 Process for the preparation of terpenes Eisai Co., Ltd. (JP) 1991-02-27 EP disclosed
JP-H0211585-A PRODUCTION OF CHROMAN DERIVATIVE EISAI CO LTD 1990-01-16 JP disclosed
US-4665244-A Chlorinated derivatives of hexadecene, their preparation and their use in the synthesis of vitamin E RHONE-POULENC SANTE (FR) 1987-05-12 US disclosed
US-4636570-A Tocopherol derivatives useful in the synthesis of vitamin E and their preparation RHONE-POULENC SANTE (FR) 1987-01-13 US disclosed