Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017143 | 0.94 | LCK (0.51) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL9017118 | 0.88 | MEN1 (0.65) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL9017071 | 0.85 | FTO (0.71) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL9017104 | 0.82 | FTO (0.53) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL10340122 | 0.80 | FTO (0.63) | FTOPABPC1LCKMEN1POLB | |
| Hydrochloric Acid SCHEMBL10340360 | 0.79 | FTO (0.62) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL9017108 | 0.78 | NTRK1 (0.43) | FTOPABPC1LCKMEN1POLB | |
| Mitonafide SCHEMBL5781995 | 0.78 | FTO (0.88) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL9017063 | 0.77 | MEN1 (0.72) | FTOPABPC1LCKMEN1POLB | |
| SCHEMBL7712243 | 0.77 | FTO (0.81) | FTOPABPC1LCKMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552544-A | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use | KNOLL AG (DE) | 1996-09-03 | — | — | US | disclosed |
| EP-0268093-B1 | 5-Nitrobenzo[de]isoquinoline-1,3 diones, their preparation and use | KNOLL AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0268093-A1 | 5-Nitrobenzo[de]isoquinoline-1,3 diones, their preparation and use | KNOLL AG (DE) | 1988-05-25 | — | — | EP | disclosed |