Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30214739 | 0.87 | L3MBTL1 (0.59) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL334927 | 0.85 | SLC1A3 (0.64) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL735799 | 0.85 | SLC1A3 (0.64) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL25413770 | 0.85 | HTT (0.68) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL334926 | 0.85 | SLC1A3 (0.64) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL7752769 | 0.84 | LMNA (0.67) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL29401172 | 0.84 | SLC1A3 (0.78) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8390660 | 0.84 | SLC1A3 (0.78) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL16269912 | 0.84 | SLC1A3 (0.62) | SLC1A3SLC1A1LMNASMN1; SMN2HTT | |
| SCHEMBL18085402 | 0.84 | SLC1A3 (0.62) | SLC1A3SLC1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537905-B1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELL PROP (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5352805-A | Reaction with a glycol; storage stability; antitumor, anticarcinogenic agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0537905-A1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0473326-A1 | Water soluble derivatives of taxol | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5059699-A | Antitumor agents; stability | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1991-10-22 | — | — | US | disclosed |