Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772413 | 0.85 | MAPT (0.37) | ACHECYP1A2MAPTFFAR1TSHR | |
| SCHEMBL7772415 | 0.81 | PTGIR (0.42) | ACHE | |
| SCHEMBL7776674 | 0.81 | PTGIR (0.42) | ACHE | |
| SCHEMBL7772412 | 0.81 | PTGIR (0.42) | ACHE | |
| SCHEMBL7713208 | 0.80 | KMT2A (0.35) | ACHEBLMTSHRSIGMAR1 | |
| SCHEMBL8486810 | 0.79 | PTGIR (0.40) | ACHE | |
| SCHEMBL7718887 | 0.76 | PTGIR (0.40) | — | |
| SCHEMBL7778663 | 0.76 | PTGIR (0.39) | ACHECYP1A2MAPTTP53 | |
| SCHEMBL7772424 | 0.76 | PTGIR (0.39) | ACHECYP1A2MAPTTP53 | |
| SCHEMBL7779781 | 0.73 | ALDH1A1 (0.37) | MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |