Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484758 | 0.84 | KMT2A (0.46) | KMT2ASIGMAR1CA1CA2ACHE | |
| SCHEMBL7495469 | 0.84 | KMT2A (0.46) | KMT2ASIGMAR1CA1CA2ACHE | |
| SCHEMBL7718887 | 0.82 | PTGIR (0.40) | — | |
| SCHEMBL9017256 | 0.80 | ACHE (0.34) | SIGMAR1BLMTSHRACHE | |
| SCHEMBL7485460 | 0.80 | ACHE (0.42) | SIGMAR1CA1CA2ACHEHTR1A | |
| SCHEMBL7776663 | 0.79 | HTR1A (0.33) | SIGMAR1ACHEHTR1AADRA1A | |
| SCHEMBL7776660 | 0.79 | HTR1A (0.33) | SIGMAR1ACHEHTR1AADRA1A | |
| SCHEMBL7772413 | 0.78 | MAPT (0.37) | TSHRACHEHTR1A | |
| SCHEMBL7713227 | 0.77 | CYP19A1 (0.37) | SIGMAR1 | |
| SCHEMBL7718891 | 0.77 | DRD2 (0.36) | SIGMAR1CA1CA2ACHEADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |