Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017289 | 0.87 | PTGER1 (0.46) | PTGER1PTGER3PTGIRPTGDRUSP2 | |
| SCHEMBL7051532 | 0.85 | PTGER1 (0.52) | PTGER1PTGER3PTGIRPTGDRUSP2 | |
| SCHEMBL9017265 | 0.84 | PTGIR (0.57) | PTGER1PTGER3PTGIRPTGDRSMN1; SMN2 | |
| SCHEMBL7777519 | 0.84 | PTGIR (0.57) | PTGER1PTGER3PTGIRPTGDRSMN1; SMN2 | |
| SCHEMBL9017268 | 0.84 | PTGIR (0.57) | PTGER1PTGER3PTGIRPTGDRSMN1; SMN2 | |
| SCHEMBL2876699 | 0.80 | RXRA (0.54) | USP2KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7776656 | 0.76 | PTGIR (0.80) | PTGER1PTGER3PTGIRPTGDRUSP2 | |
| SCHEMBL7778514 | 0.76 | PTGIR (0.80) | PTGER1PTGER3PTGIRPTGDRUSP2 | |
| SCHEMBL7778523 | 0.76 | PTGIR (0.80) | PTGER1PTGER3PTGIRPTGDRUSP2 | |
| SCHEMBL8524473 | 0.76 | PTGIR (0.45) | PTGIRUSP2ALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |