SCHEMBL9017296

SCHEMBL9017296

CCCCCCOC(C)OC(F)(F)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.44
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
FAAH O00519 7/20 0.37
CES1 P23141 6/20 0.37
NAAA Q02083 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PLA2G2C Q5R387 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559623 0.86 CES2 (0.42) CES2FAAHCES1NAAAMEN1
SCHEMBL7558553 0.79 CA1 (0.40) CES2TSHRFAAHHSD17B10PLA2G2C
SCHEMBL9061647 0.78 TP53 (0.39) TP53TSHRNAAA
SCHEMBL8659014 0.77 CES1 (0.42) CES2CES1PLA2G2C
SCHEMBL24361251 0.75 CES2 (0.52) CES2TSHRFAAHCES1NAAA
SCHEMBL24361250 0.75 CES2 (0.52) CES2TSHRFAAHCES1NAAA
SCHEMBL24361249 0.75 CES2 (0.52) CES2TSHRFAAHCES1NAAA
SCHEMBL24361246 0.75 CES2 (0.52) CES2TSHRFAAHCES1NAAA
SCHEMBL24361090 0.75 CES2 (0.52) CES2TSHRFAAHCES1NAAA
SCHEMBL11415585 0.74 CA2 (0.34) CES2S1PR1S1PR3TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-5437812-A Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-01 US disclosed