Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779776 | 0.84 | PTGIR (0.55) | PTGIRTBXAS1 | |
| SCHEMBL9017302 | 0.82 | PTGIR (0.58) | PTGIRTBXAS1 | |
| SCHEMBL7778755 | 0.78 | PTGIR (0.57) | PTGIRTBXAS1 | |
| SCHEMBL7778591 | 0.75 | PTGIR (0.66) | PTGIRTBXAS1 | |
| SCHEMBL9017314 | 0.74 | MTNR1A (0.50) | PTGIRCA1CA2ACHE | |
| SCHEMBL7778511 | 0.72 | CA1 (0.53) | PTGIRTBXAS1CA1CA2ACHE | |
| SCHEMBL9017305 | 0.72 | MTNR1A (0.48) | PTGIRCA1CA2ACHE | |
| SCHEMBL8576525 | 0.71 | PTGIR (0.62) | PTGIRTBXAS1 | |
| SCHEMBL8411111 | 0.71 | PTGIR (0.45) | PTGIRTBXAS1 | |
| SCHEMBL7778560 | 0.71 | PTGIR (0.62) | PTGIRTBXAS1CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |