Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tresperimus SCHEMBL385624 | 1.00 | FAAH (0.40) | FAAHMEN1CYP1A2KMT2APAOX | |
| Tresperimus SCHEMBL9173994 | 0.92 | HDAC6 (0.43) | FAAHMEN1CYP1A2KMT2APAOX | |
| Trifluoroacetic Acid SCHEMBL9178492 | 0.92 | HDAC6 (0.43) | FAAHMEN1CYP1A2KMT2APAOX | |
| SCHEMBL13197478 | 0.86 | PAOX (0.38) | MEN1CYP1A2KMT2APAOXSMN1; SMN2 | |
| SCHEMBL525137 | 0.84 | PAOX (0.47) | MEN1CYP1A2KMT2APAOXSMN1; SMN2 | |
| SCHEMBL524786 | 0.84 | PAOX (0.47) | MEN1CYP1A2KMT2APAOXSMN1; SMN2 | |
| Anisperimus SCHEMBL8778912 | 0.83 | FAAH (0.39) | FAAHMEN1CYP1A2KMT2ASMN1; SMN2 | |
| Anisperimus SCHEMBL8778920 | 0.83 | FAAH (0.39) | FAAHMEN1CYP1A2KMT2ASMN1; SMN2 | |
| Anisperimus SCHEMBL8778901 | 0.83 | FAAH (0.39) | FAAHMEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL8412131 | 0.83 | ACHE (0.40) | PAOXCA12CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600762-B1 | Analogues of the 15-deoxyspergualine, process for their preparation and their use as immunosuppresants | FOURNIER IND & SANTE (FR) | 1996-07-10 | — | — | EP | disclosed |
| EP-0600762-A1 | Analogues of the 15-deoxyspergualine, process for their preparation and their use as immunosuppresants | FOURNIER INDUSTRIE ET SANTE (FR) | 1994-06-08 | — | — | EP | disclosed |