Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639568 | 0.82 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8643630 | 0.79 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8643826 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8885653 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL8646249 | 0.75 | HTR2A (0.41) | CYP1A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8641029 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8643878 | 0.72 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2ALDH1A1CYP1A2 | |
| SCHEMBL8644423 | 0.72 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL8644114 | 0.71 | MEN1 (0.43) | CYP1A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9449391 | 0.71 | ATM (0.43) | MTNR1AMTNR1BALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |