Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983972 | 0.81 | KDM4E (0.77) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL15926660 | 0.78 | KDM4E (0.73) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL4143973 | 0.76 | MAPT (1.00) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL4259365 | 0.75 | KDM4E (0.69) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL29380459 | 0.73 | AHR (1.00) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL12219476 | 0.73 | AHR (1.00) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL12219478 | 0.73 | AHR (1.00) | KDM4EMAPTATMAHRALDH1A1 | |
| SCHEMBL550602 | 0.73 | AHR (1.00) | KDM4EMAPTATMAHRALDH1A1 | |
| Glycosinine SCHEMBL30839690 | 0.72 | KDM4E (0.63) | KDM4EMAPTATMAHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL3792797 | 0.70 | KDM4E (0.47) | KDM4EMAPTATMALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538825-A | Printing plate preparation process | XEROX CORPORATION (US) | 1996-07-23 | — | — | US | claimed |
| US-5102756-A | Camera speed printing plate with in situ mask | XEROX CORPORATION (US) | 1992-04-07 | — | — | US | claimed |
| US-5538825-A | Printing plate preparation process | XEROX CORPORATION (US) | 1996-07-23 | — | — | US | disclosed |
| US-5102756-A | Camera speed printing plate with in situ mask | XEROX CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |