Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SI | P14410 | 3/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | FASN | P49327 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30346436 | 0.85 | MAOA (0.69) | ALDH1A1MAPTMAPK1MGAMGAA | |
| SCHEMBL5446446 | 0.85 | MAOA (0.69) | ALDH1A1MAPTMAPK1MGAMGAA | |
| SCHEMBL15003206 | 0.82 | CYP1A2 (0.62) | ALDH1A1MAPTMAPK1GAAMAOA | |
| SCHEMBL11059079 | 0.81 | ALDH2 (0.57) | MAOAXDHALDH2MAOB | |
| SCHEMBL9838788 | 0.80 | MAOA (0.79) | ALDH1A1MAPTMGAMGAASI | |
| SCHEMBL28561297 | 0.80 | MGAM (0.54) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL10705370 | 0.80 | MAOA (0.51) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL10647142 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1GAAMAOA | |
| SCHEMBL28912778 | 0.79 | MGAM (0.56) | MGAMGAASIMGAM2MAOA | |
| SCHEMBL28336570 | 0.78 | MGAM (0.66) | ALDH1A1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8119959-A | — | — | None | — | — | JP | disclosed |
| JP-H08119959-A | XHANTHONE DERIVATIVE AND INHIBITOR OF MONOAMINE OXIDASE CONTAINING THE SAME AS ACTIVE INGREDIENT | OYO SEIKAGAKU KENKYUSHO | 1996-05-14 | — | — | JP | disclosed |