SCHEMBL9017697

SCHEMBL9017697

Cc1cn([C@H]2C[C@H](OCc3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.82

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.61
TK1 P04183 7/20 0.52
TK2 O00142 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355237 0.90 RNASE1 (0.72) RNASE1TK1TK2
SCHEMBL9017714 0.88 RNASE1 (0.63) RNASE1TK1TK2
SCHEMBL9017662 0.87 RNASE1 (0.68) RNASE1TK1TK2
SCHEMBL9017722 0.85 RNASE1 (0.63) RNASE1TK1TK2
SCHEMBL8657843 0.84 TK1 (0.54) TK1
SCHEMBL8657842 0.84 TK1 (0.54) TK1
SCHEMBL12718428 0.83 RNASE1 (0.67) RNASE1TK1TK2
SCHEMBL8742250 0.82 TK1 (0.49) RNASE1TK1TK2
SCHEMBL9017798 0.81 TK1 (0.53) RNASE1TK1
SCHEMBL8374922 0.81 RNASE1 (0.59) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0611075-B1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1996-12-18 EP disclosed
EP-0611075-A1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-08-17 EP disclosed