SCHEMBL9017765

SCHEMBL9017765

CCCCOC(=O)C1(C(=O)OCCCC)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
ATM Q13315 1/20 0.48
TSHR P16473 5/20 0.45
HPGD P15428 1/20 0.45
HCAR2 Q8TDS4 1/20 0.42
NAAA Q02083 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
ESR1 P03372 2/20 0.40
EPHX1 P07099 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 1/20 0.39
RNASEL Q05823 1/20 0.39
ACHE P22303 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16086360 0.94 NAAA (0.50) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL6058609 0.92 ALDH1A1 (0.48) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL16086396 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL17812722 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL17812506 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL17812787 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL17812746 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL17812550 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA
SCHEMBL16086201 0.92 ALDH1A1 (0.48) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL17812497 0.92 NAAA (0.53) ALDH1A1TSHRHCAR2NAAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
US-5569780-A Dialkyl 2-haloethyl malonates HULS AKTIENGESELLSCHAFT (DE) 1996-10-29 US disclosed
US-5510509-A CYCLIZATION DI-LOWER ALKYL MALONATE WITH 1,2-DICHLOROALKANE, POTASSIUM CARBONATE, DEHYDRATION BY AZEOTROPICAL DISTILLATION HULS AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5463111-A Process for preparing dialkyl 2-haloethyl malonates HULS AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
US-5192656-A Containing silveri iodide, cationic polymer; good graininess and desilvering FUJI PHOTO FILM CO., LTD. (JP) 1993-03-09 US disclosed