Methacrylic Acid

Methacrylic Acid

SCHEMBL9017974

C=C(C)C(=O)O.C=CC(=O)NC(C)(C)C

nearest known ligand 0.42

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 3/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EGFR P00533 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX1 P07099 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TGM2 P21980 1/20 0.31
LMNA P02545 2/20 0.31
TP53 P04637 1/20 0.31
ACKR3 P25106 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28072266 0.98 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Methacrylic Acid SCHEMBL28953870 0.89 ALDH1A1 (0.36) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Bicarbonate SCHEMBL8361455 0.87 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL26705 0.87
SCHEMBL7608112 0.86 TDP1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL13504152 0.86 ALDH1A1 (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Acrylic Acid SCHEMBL859634 0.85 LMNA (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL3468962 0.84 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL35506 0.84 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
Fluoride SCHEMBL21409814 0.84 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496693-A YELLOW COLOR-FORMING SILVER HALIDE EMULSION LAYER FORMED ON A SUPPORT AND CONTAINING YELLOW COLOR-FORMING COUPLER DISPERSED BY DISSOLUTION IN HIGH-BOILING ORGANIC PHOSPHORUS-OXYGEN SOLVENT, COUPLER BEING A DERIVATIVE OF MALONIC ACID DIAMIDE FUJI PHOTO FILM CO., LTD. (JP) 1996-03-05 US disclosed