Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018498 | 0.99 | P4HTM (0.55) | P4HTMHSD17B10EGFRGFERFLT1 | |
| SCHEMBL9018159 | 0.90 | KMT2A (0.49) | P4HTMKMT2AMEN1LMNA | |
| SCHEMBL9018303 | 0.88 | MCL1 (0.51) | P4HTMCXCR1CXCR2MMP1MMP2 | |
| SCHEMBL9017985 | 0.86 | P4HTM (0.66) | P4HTMHSD17B10EGFRGFERFLT1 | |
| SCHEMBL9018502 | 0.86 | GABRA5 (0.43) | P4HTMEGFRKMT2ACXCR1CXCR2 | |
| SCHEMBL9018501 | 0.86 | CXCR1 (0.42) | P4HTMEGFRCXCR1CXCR2LMNA | |
| SCHEMBL9018273 | 0.85 | LMNA (0.51) | GFERKMT2ALMNAHTT | |
| SCHEMBL9018442 | 0.85 | LMNA (0.51) | GFERKMT2ALMNAHTT | |
| SCHEMBL9018483 | 0.85 | GABRA5 (0.43) | P4HTMEGFRKMT2ACXCR1CXCR2 | |
| SCHEMBL9144067 | 0.84 | P4HTM (0.67) | P4HTMHSD17B10EGFRGFERFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |