Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018446 | 0.87 | P4HTM (0.61) | P4HTMFBP1EGFR | |
| SCHEMBL8869532 | 0.85 | P4HTM (0.45) | P2RY12P4HTMFBP1KMT2AEGFR | |
| SCHEMBL8869602 | 0.84 | ALDH1A1 (0.44) | P2RY12P4HTMFBP1KMT2AMEN1 | |
| SCHEMBL8868714 | 0.83 | P4HTM (0.45) | P2RY12P4HTMFBP1EGFR | |
| SCHEMBL9018459 | 0.82 | KMT2A (0.51) | P2RY12FBP1KMT2AMEN1PABPC1 | |
| SCHEMBL9018386 | 0.80 | MAPK1 (0.49) | MAPK1P4HTMFBP1KMT2AMEN1 | |
| SCHEMBL9018344 | 0.77 | P4HTM (0.73) | MAPK1P4HTMKMT2AMEN1KDM4E | |
| SCHEMBL8869543 | 0.77 | P4HTM (0.76) | MAPK1P4HTMKDM4EL3MBTL1EGFR | |
| SCHEMBL9574696 | 0.76 | KMT2A (0.45) | P2RY12FBP1KMT2AMEN1PABPC1 | |
| SCHEMBL9018519 | 0.75 | P4HTM (0.80) | MAPK1P4HTMKDM4EL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | claimed |
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |