Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 11/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574696 | 0.85 | KMT2A (0.45) | KMT2AMEN1PABPC1P2RY12FBP1 | |
| SCHEMBL9574681 | 0.82 | KMT2A (0.42) | KMT2AMEN1PABPC1P2RY12FBP1 | |
| SCHEMBL9018293 | 0.82 | P2RY12 (0.52) | KMT2AMEN1PABPC1P2RY12FBP1 | |
| SCHEMBL9018197 | 0.81 | MEN1 (0.43) | KMT2AMEN1FBP1EGFRMAPT | |
| SCHEMBL9018437 | 0.78 | P4HTM (0.57) | — | |
| SCHEMBL7870518 | 0.78 | P4HTM (0.64) | KMT2AMEN1EGFR | |
| SCHEMBL9018446 | 0.78 | P4HTM (0.61) | FBP1EGFR | |
| SCHEMBL8869532 | 0.76 | P4HTM (0.45) | KMT2AP2RY12FBP1EGFRCCR4 | |
| SCHEMBL9018379 | 0.76 | P4HTM (0.61) | EGFRMAPT | |
| SCHEMBL9017985 | 0.76 | P4HTM (0.66) | KMT2AMEN1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | claimed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | claimed |
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |