Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90410 | 1.00 | ALDH1A1 (0.30) | ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL28790509 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL4094838 | 0.82 | LMNA (0.37) | ALDH1A1LMNA | |
| SCHEMBL20148874 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL7777140 | 0.78 | HSD17B10 (0.33) | ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL11925999 | 0.77 | — | — | |
| SCHEMBL2037327 | 0.77 | — | — | |
| SCHEMBL13939091 | 0.77 | — | — | |
| SCHEMBL43710 | 0.76 | — | — | |
| SCHEMBL28786967 | 0.75 | USP2 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129411-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-03-06 | — | — | US | disclosed |