Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018211 | 0.94 | ALDH1A1 (0.46) | ALDH1A1POLBHSD17B10HPGDLMNA | |
| SCHEMBL9018054 | 0.92 | ACACB (0.43) | ALDH1A1POLBCA1CA2LMNA | |
| SCHEMBL9018208 | 0.92 | ALDH1A1 (0.45) | ALDH1A1POLBHSD17B10HPGDLMNA | |
| SCHEMBL9017984 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBHSD17B10HPGDLMNA | |
| SCHEMBL9018243 | 0.91 | ALDH1A1 (0.50) | ALDH1A1POLBHSD17B10HPGDLMNA | |
| SCHEMBL9018091 | 0.89 | MEN1 (0.44) | LMNARAB9AP4HTMOPRM1OPRD1 | |
| SCHEMBL9018125 | 0.89 | HSD17B10 (0.48) | ALDH1A1POLBHSD17B10CA1CA2 | |
| SCHEMBL9018167 | 0.88 | MAPT (0.48) | CA1CA2LMNARAB9A | |
| SCHEMBL9018100 | 0.88 | PPARA (0.47) | CA1CA2LMNARAB9AGAA | |
| SCHEMBL9018389 | 0.88 | LMNA (0.41) | ALDH1A1POLBHSD17B10LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |