Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018118 | 0.94 | RAB9A (0.44) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018346 | 0.92 | RAB9A (0.39) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018360 | 0.92 | RAB9A (0.50) | SMN1; SMN2RAB9AP4HTMCASP3HPGD | |
| SCHEMBL9018331 | 0.91 | RAB9A (0.40) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018325 | 0.90 | SMN1; SMN2 (0.44) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018526 | 0.90 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018202 | 0.90 | P4HTM (0.43) | MEN1KMT2AGABRA5P4HTMALDH1A1 | |
| SCHEMBL9018088 | 0.90 | RAB9A (0.50) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL9018555 | 0.89 | RAB9A (0.42) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9018126 | 0.89 | SMN1; SMN2 (0.40) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |