Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018126 | 0.97 | SMN1; SMN2 (0.40) | SMN1; SMN2FBP1EGLN1KMT2ACYP2C9 | |
| SCHEMBL9018092 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2FBP1KMT2AMEN1BCL2L1 | |
| SCHEMBL9018075 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2FBP1EGLN1KMT2AMEN1 | |
| SCHEMBL9018555 | 0.92 | RAB9A (0.42) | SMN1; SMN2FBP1KMT2AMEN1LMNA | |
| SCHEMBL9018526 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1BCL2L1MCL1 | |
| SCHEMBL9018010 | 0.91 | RAB9A (0.44) | SMN1; SMN2HTTP4HTMHPGDPAX8 | |
| SCHEMBL9018375 | 0.90 | MEN1 (0.41) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL9018404 | 0.90 | EGLN1 (0.45) | EGLN1KMT2ACYP2C9CYP2C19LMNA | |
| SCHEMBL9018465 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2CYP2C9CYP2C19MAPTHTT | |
| SCHEMBL9018346 | 0.90 | RAB9A (0.39) | SMN1; SMN2FBP1KMT2AMEN1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |