Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018291 | 0.89 | MMP1 (0.51) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL9018395 | 0.88 | MMP1 (0.61) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL9567391 | 0.86 | SMN1; SMN2 (0.58) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL9018321 | 0.86 | MMP1 (0.49) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL9018276 | 0.86 | MMP1 (0.49) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL11304619 | 0.85 | MMP1 (0.63) | MMP1MMP2MMP9TNFRSF1AMAOA | |
| SCHEMBL11304615 | 0.85 | MMP1 (0.63) | MMP1MMP2MMP9TNFRSF1AMAOA | |
| SCHEMBL9018426 | 0.84 | KDM4E (0.44) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL9018405 | 0.84 | HDAC3 (0.54) | MMP1MMP2MMP9TNFRSF1AKDM4E | |
| SCHEMBL9018355 | 0.83 | MMP1 (0.65) | MMP1MMP2MMP9MAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600949-B1 | NEW 3,5-DI-TERT.BUTYL-4-HYDROXYPHENYL DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0527458-A1 | New 3,5-di-tert.-butyl-4-hydroxyphenyl derivatives, process for their preparation and pharmaceutical compounds | Roche Diagnostics GmbH (DE) | 1993-02-17 | — | — | EP | disclosed |