Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577736 | 0.77 | HDAC8 (0.67) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL5455838 | 0.71 | — | — | |
| SCHEMBL6238003 | 0.71 | HDAC8 (0.67) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL5831783 | 0.69 | HDAC8 (0.95) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Iodide SCHEMBL7051892 | 0.69 | HDAC8 (0.95) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Iodide SCHEMBL23131037 | 0.69 | HDAC8 (0.95) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Iodide SCHEMBL23131038 | 0.69 | HDAC8 (0.95) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL8336432 | 0.65 | HDAC8 (0.69) | HDAC8TSHR | |
| SCHEMBL23131039 | 0.64 | HDAC8 (0.82) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL31034828 | 0.61 | HDAC8 (0.75) | HDAC8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748825-A2 | Ethylene-alpha-olefin-non-conjugated diene copolymer rubber | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |