Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018200 | 0.95 | ALDH1A1 (0.48) | HSD17B10ALDH1A1KMT2APKMGAA | |
| SCHEMBL9018292 | 0.93 | HSD17B10 (0.48) | HSD17B10ALDH1A1STSSMN1; SMN2 | |
| SCHEMBL9018151 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1STSLMNA | |
| SCHEMBL9018051 | 0.90 | ALDH1A1 (0.45) | ALDH1A1RAB9AKMT2AHDAC3HDAC4 | |
| SCHEMBL9018322 | 0.90 | HSD17B10 (0.48) | HSD17B10ALDH1A1STSLMNA | |
| SCHEMBL9018453 | 0.90 | HSD17B10 (0.48) | HSD17B10ALDH1A1STSRAB9AGAA | |
| SCHEMBL9018387 | 0.90 | STS (0.48) | HSD17B10ALDH1A1STSRAB9AKMT2A | |
| SCHEMBL9018529 | 0.90 | STS (0.48) | HSD17B10ALDH1A1STSRAB9AKMT2A | |
| SCHEMBL9018078 | 0.89 | ACACB (0.48) | ALDH1A1KMT2ASMN1; SMN2LMNATP53 | |
| SCHEMBL9018125 | 0.89 | HSD17B10 (0.48) | HSD17B10ALDH1A1STSRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |