Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018477 | 1.00 | KMT2A (0.49) | KMT2AEPHX2GAAAURKATPX2 | |
| SCHEMBL6191252 | 0.83 | NR4A1 (0.51) | ALDH1A1 | |
| SCHEMBL6191253 | 0.83 | NR4A1 (0.51) | ALDH1A1 | |
| SCHEMBL9683421 | 0.82 | KMT2A (0.41) | KMT2AALDH1A1 | |
| SCHEMBL9683417 | 0.82 | KMT2A (0.41) | KMT2AALDH1A1 | |
| SCHEMBL9685241 | 0.80 | TDP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL10792060 | 0.80 | TDP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL8228620 | 0.80 | TDP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL23493346 | 0.75 | EPHX2 (0.57) | KMT2AEPHX2GAAAURKATPX2 | |
| SCHEMBL10339425 | 0.75 | EPHX2 (0.57) | KMT2AEPHX2GAAAURKATPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563280-A | CONTROLLING MONOCOTYLEDENOUS WEEDS IN CROPS | AMERICAN CYANAMID CO. (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0694257-A1 | 4-Phenoxycoumarins and thio derivatives thereof, their preparation and use as herbicides | AMERICAN CYANAMID COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |