Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683421 | 1.00 | KMT2A (0.41) | KMT2APPARGPPARAATMKDM4E | |
| SCHEMBL10792060 | 0.82 | TDP1 (0.42) | ATMKDM4EALDH1A1ALOX15 | |
| SCHEMBL9685241 | 0.82 | TDP1 (0.42) | ATMKDM4EALDH1A1ALOX15 | |
| SCHEMBL8228620 | 0.82 | TDP1 (0.42) | ATMKDM4EALDH1A1ALOX15 | |
| SCHEMBL9018474 | 0.82 | KMT2A (0.49) | KMT2AALDH1A1 | |
| SCHEMBL9018477 | 0.82 | KMT2A (0.49) | KMT2AALDH1A1 | |
| SCHEMBL6191253 | 0.82 | NR4A1 (0.51) | PPARGPPARANR4A2ALDH1A1CYP11B1 | |
| SCHEMBL6191252 | 0.82 | NR4A1 (0.51) | PPARGPPARANR4A2ALDH1A1CYP11B1 | |
| SCHEMBL4253707 | 0.76 | GAA (0.51) | KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4253701 | 0.76 | GAA (0.51) | KMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171865-A | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0331078-A2 | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |