Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018121 | 0.94 | PTGDR (0.44) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7874566 | 0.89 | MAPT (0.43) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL9143088 | 0.89 | KMT2A (0.43) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7867910 | 0.88 | PTGDR2 (0.45) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL8869975 | 0.87 | EGLN1 (0.44) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL9018555 | 0.86 | RAB9A (0.42) | MAPTKMT2AL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7869470 | 0.86 | PTGDR (0.44) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7874624 | 0.86 | PTGDR (0.42) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL9018317 | 0.86 | HPGD (0.43) | PTGDRPTGDR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL9018491 | 0.86 | MAPT (0.40) | MAPTKMT2AL3MBTL1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |