Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921655 | 0.90 | GHSR (0.45) | GHSRNAALAD2MMEMAOB | |
| SCHEMBL8922575 | 0.88 | GHSR (0.48) | GHSRNAALAD2TRPV1MMEERCC5 | |
| SCHEMBL8922585 | 0.88 | GHSR (0.48) | GHSRNAALAD2TRPV1MMEERCC5 | |
| SCHEMBL8923880 | 0.82 | GHSR (0.46) | GHSRNAALAD2MMEMAOB | |
| SCHEMBL8922494 | 0.82 | GHSR (0.46) | GHSRNAALAD2MMEMAOB | |
| SCHEMBL8923105 | 0.80 | GHSR (0.46) | GHSRNAALAD2TRPV1MME | |
| SCHEMBL8923115 | 0.80 | GHSR (0.46) | GHSRNAALAD2TRPV1MME | |
| SCHEMBL8920614 | 0.77 | GHSR (0.58) | GHSRNAALAD2 | |
| SCHEMBL8921747 | 0.77 | GHSR (0.58) | GHSRNAALAD2 | |
| SCHEMBL3703216 | 0.74 | GHSR (0.46) | GHSRNAALAD2CNR2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |