Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018103 | 0.92 | P4HTM (0.45) | P4HTMGABRA5GRNSORT1CASP1 | |
| SCHEMBL9018334 | 0.85 | P4HTM (0.58) | P4HTM | |
| SCHEMBL9139287 | 0.85 | P4HTM (0.52) | P4HTMPDCD1CD274CASP1 | |
| SCHEMBL9018452 | 0.80 | MCL1 (0.55) | P4HTM | |
| SCHEMBL7869169 | 0.80 | GABRA5 (0.44) | P4HTMGABRA5 | |
| SCHEMBL9018262 | 0.79 | SMN1; SMN2 (0.52) | P4HTM | |
| SCHEMBL9018035 | 0.78 | P4HTM (0.58) | P4HTMGABRA5 | |
| SCHEMBL9018410 | 0.78 | P4HTM (0.47) | P4HTMGABRA5 | |
| SCHEMBL9018143 | 0.77 | SCN3A (0.48) | P4HTM | |
| SCHEMBL9142936 | 0.77 | P4HTM (0.55) | P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |