Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 10/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869455 | 0.86 | P4HTM (0.57) | GABRA5P4HTM | |
| SCHEMBL9574775 | 0.85 | P4HTM (0.59) | GABRA5P4HTM | |
| SCHEMBL7867915 | 0.85 | ALKBH2 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8869193 | 0.84 | P4HTM (0.54) | P4HTMAGTR1AGTR2 | |
| SCHEMBL9574694 | 0.84 | MEN1 (0.47) | — | |
| SCHEMBL9018103 | 0.83 | P4HTM (0.45) | GABRA5P4HTMAGTR2 | |
| SCHEMBL7871645 | 0.81 | P4HTM (0.58) | GABRA5P4HTM | |
| SCHEMBL9018571 | 0.80 | P4HTM (0.42) | GABRA5P4HTM | |
| SCHEMBL7869457 | 0.80 | P4HTM (0.47) | P4HTM | |
| SCHEMBL7871640 | 0.80 | RAB9A (0.52) | P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |