Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8393799 | 0.98 | SLC9A1 (0.51) | SLC9A1KAT6ACTSSTAS1R3TAS1R1 | |
| SCHEMBL8609816 | 0.89 | SLC9A1 (0.45) | SLC9A1KAT6ACTSSTAS1R3TAS1R1 | |
| SCHEMBL9018664 | 0.84 | SLC9A1 (0.56) | SLC9A1HTR2BHTR7LMNAGAA | |
| Hydrochloric Acid SCHEMBL8393907 | 0.83 | SLC9A1 (0.54) | SLC9A1HTR2BHTR7CNR2LMNA | |
| SCHEMBL477444 | 0.81 | KAT6A (0.49) | KAT6ACTSSTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9018684 | 0.77 | HTR2B (0.39) | SLC9A1P2RX7HTR2BHTR7GAA | |
| SCHEMBL28188796 | 0.77 | KAT6A (0.51) | KAT6ACTSSTAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL8390861 | 0.76 | SLC9A1 (0.51) | SLC9A1HTR2BHTR7 | |
| SCHEMBL9560994 | 0.75 | KAT6A (0.50) | KAT6ACTSSTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL398909 | 0.75 | KAT6A (0.54) | KAT6ACTSSTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |