Sugi Predict

Sugi Predict / Compounds / SCHEMBL398909

SCHEMBL398909

SCHEMBL398909

O=C(O)c1cccc(C(F)(F)F)c1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 2/20 0.54
▸ TAS2R14 Q9NYV8 2/20 0.51
▸ FABP4 P15090 1/20 0.50
▸ CTSS P25774 1/20 0.49
▸ TAS1R3 Q7RTX0 1/20 0.48
▸ TAS1R1 Q7RTX1 1/20 0.48
▸ TAS1R2 Q8TE23 1/20 0.48
▸ LMNA P02545 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ ALB P02768 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ ALOX15 P16050 1/20 0.44
▸ DHODH Q02127 1/20 0.44
▸ HDAC6 Q9UBN7 1/20 0.44
▸ HDAC8 Q9BY41 1/20 0.44
▸ P2RX7 Q99572 1/20 0.44
▸ NOTUM Q6P988 1/20 0.43
▸ KCNK3 O14649 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL27618285 0.91 KAT6A (0.51) KAT6ATAS2R14FABP4CTSSTAS1R3
SCHEMBL28188796 0.86 KAT6A (0.51) KAT6ATAS2R14CTSSTAS1R3TAS1R1
SCHEMBL25212753 0.84 TAS2R14 (0.47) KAT6ATAS2R14FABP4CTSSTAS1R3
SCHEMBL28310940 0.84 KDM4E (0.47) KAT6ATAS2R14FABP4CTSSTAS1R3
SCHEMBL9560994 0.84 KAT6A (0.50) KAT6ATAS2R14CTSSTAS1R3TAS1R1
SCHEMBL28160264 0.84 ALDH1A1 (0.50) KAT6ATAS2R14FABP4LMNAGAA
SCHEMBL283643 0.82 KAT6A (0.49) KAT6ATAS2R14CTSSTAS1R3TAS1R1
SCHEMBL477444 0.82 KAT6A (0.49) KAT6ACTSSTAS1R3TAS1R1TAS1R2
SCHEMBL377350 0.82 CTSS (0.51) KAT6ATAS2R14CTSSTAS1R3TAS1R1
SCHEMBL29723227 0.82 CTSS (0.51) KAT6ATAS2R14CTSSTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 — — CN claimed
CN-117567298-A Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine 上海馨远医药科技有限公司 2024-02-20 — — CN claimed
CN-111848832-B Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2024-02-20 — — CN claimed
CN-111892667-B Application of fluorine-containing compound modified cationic polymer in preparation of medical cosmetic and health care products 苏州大学 2024-02-20 — — CN claimed
CN-111848831-B Application of fluorine-containing compound modified cationic polymer in preparation of vaccine medicine 苏州大学 2023-06-13 — — CN claimed
CN-115448835-A Synthetic method of 2-fluoro-3- (trifluoromethyl) benzoic acid 苏州莱克施德药业有限公司 2022-12-09 — — CN claimed
EP-4095162-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER Soochow University (CN) 2022-11-30 — — EP claimed
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD SOOCHOW UNIVERSITY (CN) 2022-09-01 — — US claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 — — US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 — — US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 — — US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed
EP-0607826-B1 Fluoro-trifluoromethylbenzoic acid derivatives BAYER AG (DE) 1997-05-07 — — EP claimed
US-5493048-A REACTING METALLIZED FLUORO-TRIFLUOROMETHYLBENZENE DERIVATIVE WITH CARBON DIOXIDE AND PRODUCT IS THEN HYDROLYSED WITH AN ACID TO FORM ACID, SIMILARLY HALOGENATION GIVE ACID HALIDE AND WITH ALCOHOL GIVES ESTER BAYER AKTIENGESELLSCHAFT (DE) 1996-02-20 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD F12, SLCO4C1, SLC7A1 KAT6A 472/4885TAS2R14 406/4885FABP4 889/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 KAT6A 2429/4885TAS2R14 2694/4885FABP4 3213/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 KAT6A 163/4885TAS2R14 1665/4885FABP4 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.