Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 11/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018661 | 0.90 | PLAU (0.44) | PLAUSLC9A1KCNH2ADRA1DHTR2A | |
| SCHEMBL8610545 | 0.89 | NOTUM (0.47) | PLAUSLC9A1KCNH2 | |
| SCHEMBL9018681 | 0.86 | SLC9A1 (0.54) | SLC9A1KCNH2 | |
| SCHEMBL9018687 | 0.84 | SLC9A1 (0.41) | PLAUSLC9A1KCNH2 | |
| SCHEMBL9018678 | 0.84 | SLC9A1 (0.45) | PLAUSLC9A1KCNH2SLC9A2 | |
| SCHEMBL9018731 | 0.82 | SLC9A1 (0.42) | PLAUSLC9A1KCNH2 | |
| SCHEMBL8613931 | 0.81 | NOTUM (0.47) | PLAUSLC9A1KCNH2 | |
| SCHEMBL8611003 | 0.79 | NOTUM (0.48) | SLC9A1KCNH2 | |
| SCHEMBL9018711 | 0.77 | PLAU (0.41) | PLAUSLC9A1KCNH2 | |
| SCHEMBL8612363 | 0.77 | NOTUM (0.43) | SLC9A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |